I have always struggled with jet-lag. For 50 years I have traveled back and forth over the Atlantic, and if anything, it has gotten worse with age. I have tried all sorts of tricks, from taking melatonin, to slowly shifting my sleep schedule before traveling, to drugging myself with sleeping pills. Nothing has worked that well…… until I tried these tablets. I flew West from the EU to the US a few weeks ago, and took the tablets, as directed, and i had NO JET LAG. I kept waiting for it to hit, and it didn’t. For the first time in my life! So I immediately ordered 3 more boxes. Flying back East, especially to Scandinavia in winter, I did notice a bit more jet lag, but I also did not take them every 2 hours as I was sleeping much of the way back, so perhaps that made a difference. Anyways, I strongly recommend these and i am grateful for this game-changer.